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DNAGinkgo+PlatformTWSTTwist+SynthesisABSIAbsci+AIDesignCRSPCRISPR Therapeutics+EditBEAMBeam+BaseEditNTLAIntellia+InVivoCRBUCaribou+CellTherapyRXRXRecursion+AIILMNIllumina+SeqEDITEditas+GeneFUND.YTD2025$17.3B.Raised

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Real-time intelligence on synbio and synbio funding, regulatory milestones, deployments, and policy.

Aug 6, 2026BREAKING

CEX Chromatography Reclaims Its Role in mAb Purification

Cation exchange chromatography is back at center stage as rising mAb titers overwhelm standard affinity capture purity thresholds.

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Aug 5, 2026BREAKING

Child Dies in HuidaGene CRISPR Trial, China Transparency Under Fire

A child died in HuidaGene's CRISPR trial for Duchenne MD. China's investigator-led pathway kept it hidden for 15 months.

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Aug 5, 2026RESEARCH

Rotating Drum Bioreactor Hits 1.3 g/L mAb Titer

ENEA's rotating drum bioreactor hit 1.3 g/L mAb titer vs 0.71 g/L in stirred-tank — nearly doubling yield by solving oxygen transfer limits.

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Aug 5, 2026BREAKING

Confluence Genetics' Cas-CLEAR Targets Cancer Cells

Confluence Genetics' Cas-CLEAR uses a non-editing CRISPR mechanism to destroy cells with specific genetic signatures.

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Aug 4, 2026BREAKING

Aurora Therapeutics Folds 7 Months After Launch

Aurora Therapeutics scraps its lead custom CRISPR program and cuts staff just 7 months after launch, undercut by Beam Therapeutics.

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Jul 31, 2026BREAKING

Allogene's cema-cel Wins RMAT and Fast Track for LBCL

FDA grants RMAT and Fast Track to Allogene's allogeneic CD19 CAR-T; Sail and J&J partner on in vivo CAR-T for autoimmune disease.

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Jul 31, 2026BREAKING

ARPA-H Funds AEGIS $27.7M to Edit Childhood Immune Disorders

ARPA-H awards IGI-led AEGIS consortium $27.7M to build a platform for personalised in vivo gene editing in paediatric immune disorders.

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Jul 29, 2026RESEARCH

UIUC Base Editors Cut HTT Toxic Fragments in Mice

UIUC scientists screened 140+ base editors to disrupt HTT exon 13 splicing, reducing toxic fragments in Huntington's mouse models.

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Jul 28, 2026BREAKING

ElevateBio Locks In 98% miv-cel Manufacturing Rate for Kyverna

ElevateBio and Kyverna sign commercial supply deal for miv-cel CAR T, citing a >98% clinical manufacturing success rate.

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Jul 27, 2026BREAKING

AAV Base Editing Trial Kills Child After Ethics Failures

A six-year-old died from thrombotic microangiopathy 7 days after dual-AAV9 base editing for a nonfatal syndrome, Science reports.

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Jul 24, 2026BREAKING

AI Designs CRISPR Nucleases 30% Divergent From Nature

Two studies use AI to redesign CRISPR nucleases, with one producing proteins ~30% divergent from natural Cas12 sequences.

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Jul 24, 2026BREAKING

China Concealed Child's Death in Gene Editing Trial

A six-year-old died seven days after a brain-targeted base editing trial in Shanghai. The death was concealed from global registries.

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Jul 23, 2026BREAKING

All G Enters US Market with Sub-5% Iron Lactoferrin

Australian startup All G enters the US with precision-fermented apo-lactoferrin at below 5% iron saturation, produced at 60,000-liter scale.

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Jul 21, 2026RESEARCH

UCSD Joins IGI as Fourth UC CRISPR Partner

UC San Diego joins IGI as its fourth UC partner, adding marine science and AMR drug discovery to a network backed by $80M+ in recent grants.

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Jul 21, 2026BREAKING

IGI Adds UCSD as 4th UC Partner for CRISPR Expansion

UC San Diego joins IGI as its fourth UC partner campus, expanding CRISPR applications in ocean science, microbiome, and antimicrobial resistance.

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Jul 21, 2026BREAKING

Immitra Bio Raises CHF 2.4M for In-Vivo Gene Editing

ETH Zurich spinout Immitra Bio closes CHF 2.4M pre-seed to develop mutation-agnostic in-vivo gene editing for inherited anemias.

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Jul 20, 2026BREAKING

FDA Clears Casgevy CRISPR Therapy for Children Age 2+

FDA extends Casgevy's sickle cell indication to patients as young as 2, adding ~5,500 eligible American children.

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Jul 17, 2026RESEARCH

AI-Designed TnpB Hits 50% Editing in Human Cells

AI-designed SynTnpB enzymes hit 50% editing efficiency in human cells vs. 28% for natural TnpB, per Science study.

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Jul 16, 2026BREAKING

AI-Designed CRISPR Nucleases Match Natural Enzymes in Cells

UC Berkeley team uses ESM Inverse Folding + evolution constraints to build synthetic nucleases at 72–83% sequence divergence from nature.

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Jul 16, 2026BREAKING

ADM Scales Every's OvoPro via Precision Fermentation

ADM partners with Every to scale OvoPro egg protein via precision fermentation, as orders surge 550% year-over-year in early 2026.

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